Integrative Exercise Physiology Laboratory

Human Research

• Development of Hypoxic Exercise Training Program for the Elderly Humans with Impaired Microvascular Function: Pilot Study 

  • Source: External funds (NRF: 2019R1F1A1062693, 2019-2022, PI: Chansol Hurr)

  • Description: In this project, our lab is trying to find an effective and applicable exercise training strategy to improve blunted microvascular function in the elderly humans. For this aim, cutaneous microdialysis technique is used for the assessment of microvascular function. 

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• Conditioning for Exercise Performance and Recovery Strategy

  • Source: Internal funds (JBNU, PI: Chansol Hurr)

  • Description: This project develops optimal and applicable conditioning strategies before or during exercise. Also, we assess various recovery methods from the perspective of cardiovascular and metabolic system in our body. The ultimate goal of this project is to apply the developed strategies to the elite athletes of diverse sports for their maximal performance and minimal risks of injury.

Animal Research

• Exercise Effects of Autophagy in Skeletal Muscle during Type 1 Diabetes 

  • Source: Internal funds (JBNU, PI: Chansol Hurr)

  • Description: We investigate mechanisms underlying autophagic alterations in skeletal muscle during diabetes and how aerobic exercise training improves metabolic dysfunction. We utilize various techniques including Western Blot, ELISA, IHC, basic histology, and micro-surgery on C57BL/6 mice and Sprague Dawley rats.

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• Mechanistic Approach for Findings from Human Research

  • Source: Internal funds (JBNU, PI: Chansol Hurr)

  • Description: We use animal models to investigate mechanisms that are found in human research. Our current project in this category investigates mechanisms as to how cooling recovery reduces exercise-induced increase in plasma lactate.

Past Projects

• Role of Brain Toll Like Receptor 4 in Obesity-Induced Hypertension 

  • Source: External funds (American Heart Association (AHA), 18POST33990225, 2018-2021, PI: Chansol Hurr

  • Description​: This project investigates roles of TLR4 in the subfornical organ (SFO); a unique CNS nuclei that is situated outside of the blood-brain barrier. Overall aim is to test the hypothesis that an SFO TLR4-ROS-NFkB network mediates sympathetic overactivity and hypertension during obesity.

  • This funded project was relinquished due to job (lab) transfer